Among breast cancer patients who have an early, noninvasive form of the disease - called ductal carcinoma in situ, or DCIS - those whose breast tissue is the densest have the highest risk of facing a recurrence of their disease.
Women who previously had DCIS in one breast had three times the risk of developing cancer in the opposite breast, if their breast tissue had the greatest density among women in the study, compared with women in the study whose breast tissue was the least dense.
Women with densest breast tissue also had about one-and-a-half times the risk of developing cancer in the same breast, and two times the risk of developing invasive cancer in either breast, than women with the least dense breast tissue.
Research is based on Kaiser study on a group of 935 women whose previous DCIS had been treated with breast-conserving surgery (not a mastectomy). The density of breast tissue was assessed from mammograms.
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